The effect of Kombucha extract on plasma lipoproteins and liver enzymes in male wistar rats
Parichehreh Yaghmaei, Kazem Parivar, L Karkhane
Introduction: Cardiac and blood vessel diseases are major problems in developed and developing countries. The most important cause of these diseases is atherosclerosis the high density of plasma lipids is considered the main factor in its appearance and development. The aim of this study was to investigate the effect of kombucha extract on plasma lipoproteins and liver enzymes in male Wi star rats. Materials and Methods: Animals were divided into 4 groups: l) Control group, which received normal water and food diet.2) Sham group which received water and high-fat diet (included: 66.5g carbohydrate, 20.lg fat, and 4.49g protein).3) Experimental group 1 received a high-fat diet and kombucha extract.4) Experimental group 2, received food diet and kombucha extract. The kombucha extract was poured in a container and was put in access to the animals. The duration of the treatment has been continued for 8 weeks. After weighting, the animals were anesthetized with ether. After treatment for 8 weeks, blood serum was prepared, and the concentrations of triglyceride, cholesterol, plasma lipoproteins, and liver enzymes such as AST and ALT were measured. Results: The results showed that the serum level of cholesterol, LDL, AST, and ALT in both experimental groups had no significant decrease as compared with a control group, but serum level of HDL had decreased significantly as compared to the control group (p<0.05). On the other hand, the serum level of TG in both experimental groups indicated significant decreases as compared to the control group (p<0.001). Conclusion: The use of the kombucha extract can decrease triglyceride and increase HDL serum. Therefore this extract might be used in treating diseases such as cardiac and blood vessel diseases.
Keywords: cholesterol, liver, protein, rats
Citation: JOURNAL OF FOOD TECHNOLOGY AND NUTRITION SPRING 2012 , Volume 9 , Number 2 (34); Page(s) 29 To 36.
Study Mailing Address:
DEPARTMENT OF BIOLOGY, SCIENCE AND RESEARCH BRANCH, ISLAMIC AZAD UNIVERSITY, TEHRAN, IRAN
Date Updated: March 28, 2020