The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats
Hemmat Maghsoudi, Hussein Benagozar Mohammadi
Background: Peritoneal adhesions are fibrous bands of tissues formed between organs that are normally separated and/or between organs and the internal body wall after peritoneal injury. The aim of the study was to investigate the effect of intra-peritoneal administration of Kombucha on intra-peritoneal adhesions. Materials and methods: Eighty Wistar rats were subjected to standardized lesion by scraping model and were randomly divided into two groups. Group I received no treatment, and Group II received 15 ml of Kombucha solution intra-peritoneally. On the post-operative 14th day adhesion intensity score, inflammatory cell reaction, and the number of adhesion bands were determined. Results: In the control group, there were no rats with grade 0, and I adhesions. In group II, there were 26 rats (78.8%) with grade 0-2 adhesions. Adhesion intensity was significantly less in group II (P<0.0001). The number of adhesion bands was significantly less in group II (P<0.001). Conclusion: It was concluded that the intra-peritoneal administration of Kombucha might be useful for preventing peritoneal adhesions.
Keywords: peritoneal, adhesions, kombucha, prevention, rats
Citation: Indian Journal of Surgery April 2009, Volume 71, Issue 2, pp 73-77
Study Mailing Address:
Department of Surgery, Faculty of Medicine, University of Medical Sciences of Tabriz, Tabriz, Iran
Date Updated: February 16, 2021